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CGT Match

The Carrier Screening Test from Igenomix provides a powerful and exclusive computerized tool called CGT Match. This software allows genetically matched gametes to be selected for a recipient after analyzing the egg or sperm bank of an assisted reproduction clinic.

This unique system allows the clinic the opportunity make a bank available which has been pre-screened for more than 600 genetic diseases. This includes Cystic Fibrosis and Fragile X Syndrome which have a high prevalence in this group of diseases.

How does it work?

A bank of genetically-tested eggs or sperm must be available:

  1. Perform a karyotype to identify any chromosomal abnormalities.
  2. Carry out the Carrier Screening Test on all of the donors. After completing both tests the donor bank will be genetically tested.
  3. The Carrier Screening Test is performed on the patient who is using their own gamete.
  4. Once donors are tested, as well as the person who contributes their own gamete, our CGTMatch program performs a search to assign a compatible donor whose mutations do not match those of the patient.

Data Results

Igenomix Match allows you to use any donor even if they carry pathogenic genes.

Clinical Incompatibility

In our last study (of 85 couples) we found that 5% are incompatible:

  • Haemophilia A (F8 gene)
  • Smith-Lemli-Opitz (DHCR7 gene)
  • Polycystic Kidney disease (Recessive; PKHD1 gene)
  • Fragile X (FMR1 gene)
  • Cystic fibrosis (CFTR gene)
  • Retinitis pigmentosa (Blindness; ABCD4 gene)
More information
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